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Development and clinical trial of a novel bioactive bone cement

LEONG John, LI Zhaoyang, LU William

《医学前沿(英文)》 2008年 第2卷 第2期   页码 117-126 doi: 10.1007/s11684-008-0022-1

摘要: Strontium (Sr) and related compounds have become more attractive in the prevention and treatment of osteoporosis. Previously, we developed a novel bioactive bone cement which is mainly composed of strontium-containing hydroxyapatite (Sr-HA) filler and bisphenol A diglycidylether dimethacrylate (Bis-GMA) resin. This bone cement is superior to conventional polymethylmethacrylate (PMMA) bone cement in bioactivity, biocompatibility, and osseointegration. It also has shown sufficient mechanical strength properties for its use in percutaneous vertebroplasty (PVP) and total hip replacement (THR). In this paper, we review the and clinical evidence for the effectiveness of this bioactive bone cement.

关键词: bioactivity     effectiveness     strontium-containing hydroxyapatite     osseointegration     sufficient mechanical    

Sufficient downward rotation of the christa philtri on the cleft side: a modified technique

null

《医学前沿(英文)》 2013年 第7卷 第4期   页码 510-516 doi: 10.1007/s11684-013-0299-6

摘要:

Cleft lip and palate (CLP) is the most common craniofacial congenital deformity. The etiology of CLP is multifactorial and involves complex interactions between environmental and genetic factors. Millard’s rotation-advancement technique has long been considered as state-of-the-art for unilateral cleft lip repair. However, this method may leave the christa philtri on the cleft side insufficiently downward rotated, especially in wide complete clefts. In this study, we introduce a modified technique to better rotate the christa philtri on the cleft side down. The skin, muscle, and mucosa in the deformed region were dissected and separately maneuvered. Sixty patients with unilateral complete cleft lip and palate were operated with this technique. The lip height, lip length, and relative height of the christa philtri were measured for symmetry evaluation. No significant difference was observed between the relative height of the christa philtri on both sides, either immediate (P= 0.214) or 10 months after surgery (P = 0.344). The difference observed in the lip height and lip length immediately after surgery became statistically insignificant after 10 months (P = 0.104 for lip height and 0.121 for lip length). These results suggested that sufficient and stable downward rotation of the christa philtri on the cleft side can be achieved using our technique.

关键词: cleft lip and palate     rotation advancement     sufficient rotation     christa philtri geometrically justified    

A bionic approach for the mechanical and electrical decoupling of an MEMS capacitive sensor in ultralow

《机械工程前沿(英文)》 2023年 第18卷 第2期 doi: 10.1007/s11465-023-0747-1

摘要: Capacitive sensors are efficient tools for biophysical force measurement, which is essential for the exploration of cellular behavior. However, attention has been rarely given on the influences of external mechanical and internal electrical interferences on capacitive sensors. In this work, a bionic swallow structure design norm was developed for mechanical decoupling, and the influences of structural parameters on mechanical behavior were fully analyzed and optimized. A bionic feather comb distribution strategy and a portable readout circuit were proposed for eliminating electrostatic interferences. Electrostatic instability was evaluated, and electrostatic decoupling performance was verified on the basis of a novel measurement method utilizing four complementary comb arrays and application-specific integrated circuit readouts. An electrostatic pulling experiment showed that the bionic swallow structure hardly moved by 0.770 nm, and the measurement error was less than 0.009% for the area-variant sensor and 1.118% for the gap-variant sensor, which can be easily compensated in readouts. The proposed sensor also exhibited high resistance against electrostatic rotation, and the resulting measurement error dropped below 0.751%. The rotation interferences were less than 0.330 nm and (1.829 × 10−7)°, which were 35 times smaller than those of the traditional differential one. Based on the proposed bionic decoupling method, the fabricated sensor exhibited overwhelming capacitive sensitivity values of 7.078 and 1.473 pF/µm for gap-variant and area-variant devices, respectively, which were the highest among the current devices. High immunity to mechanical disturbances was maintained simultaneously, i.e., less than 0.369% and 0.058% of the sensor outputs for the gap-variant and area-variant devices, respectively, indicating its great performance improvements over existing devices and feasibility in ultralow biomedical force measurement.

关键词: micro-electro-mechanical system capacitive sensor     bionics     operation instability     mechanical and electrical decoupling     biomedical force measurement    

Process evaluation of an alternating aerobic-anoxic process applied in a sequencing batch reactor for nitrogen removal

ZENG Wei, PENG Yongzhen, WANG Shuying

《环境科学与工程前沿(英文)》 2007年 第1卷 第1期   页码 28-32 doi: 10.1007/s11783-007-0005-5

摘要: In order to improve the nitrogen removal efficiency and save operational cost, the feasibility of the alternating aerobic-anoxic process (AAA process) applied in a sequencing batch reactor (SBR) system for nitrogen removal was investigated. Under sufficient influent alkalinity, the AAA process did not have an advantage over one aerobicanoxic (OAA) cycle on treatment efficiency because microorganisms had an adaptive stage at the alternating aerobic-anoxic transition, which would prolong the total cycling time. On the contrary, the AAA process made the system control more complicated. Under deficient influent alkalinity, when compared to OAA, the AAA process improved treatment efficiency and effluent quality with NH-N in the effluent below the detection limit. In the nitrification, the average stoichiometric ratio between alkalinity consumption and ammonia oxidation is calculated to be 7.07 mg CaCO/mg NH-N. In the denitrification, the average stoichiometric ratio between alkalinity production and NO-N reduction is about 3.57 mg CaCO/mg NO-N. As a result, half of the alkalinity previously consumed during the aerobic nitrification was recovered during the subsequent anoxic denitrification period. That was why the higher treatment efficiency in the AAA process was achieved without the supplement of bicarbonate alkalinity. If the lack of alkalinity in the influent was less than 1/3 of that needed, there is no need for external alkalinity addition and treatment efficiency was the same as that under sufficient influent alkalinity. Even if the lack of alkalinity in the influent was more than 1/3 of that needed, the AAA process was an optimal strategy because it reduced the external alkalinity addition and saved on operational cost.

关键词: bicarbonate alkalinity     sufficient influent     influent alkalinity     detection     alkalinity production    

新的充分条件和哈密尔顿图

赵克文

《中国工程科学》 2003年 第5卷 第11期   页码 61-64

摘要:

记δ和α分别表示图G的最小度和独立数,1991年Faudree等人得到图G不相邻的任意2点x,y均有|N(x)∪N(y)|≥n-δ的Hamiltonian结果。1993年美国乔治亚州立大学的陈冠涛教授深化Fan条件并且得到满足1≤|N (x)∩N(y)|≤α-1的不相邻的任2点x,y均有max{d(x),d(y)}≥n/2的Hamiltonian结果。进一步改进Faudree等人的条件和综合陈冠涛教授的思路,研究满足1≤|N(x)∩N(y)|≤α-1的不相邻的任2点x,y均有|N(x)∪N(y)|≥n-δ-1,则是哈密尔顿图或G∈{K(n-1)/2, (n + 1)/2, K2* V3K(n-2)/3}。

关键词: 哈密尔顿图     邻域并     最小度     独立数    

Determination of mechanical parameters for elements in meso-mechanical models of concrete

Xianglin GU, Junyu JIA, Zhuolin WANG, Li HONG, Feng LIN

《结构与土木工程前沿(英文)》 2013年 第7卷 第4期   页码 391-401 doi: 10.1007/s11709-013-0225-7

摘要: The responses of cement mortar specimens of different dimensions under compression and tension were calculated based on the discrete element method with the modified-rigid-body-spring concrete model, in which the mechanical parameters derived from macro-scale material tests were applied directly to the mortar elements. By comparing the calculated results with those predicted by the Carpinteri and Weibull size effects laws, a series of formulas to convert the macro-scale mechanical parameters of mortar and interface to those at the meso-scale were proposed through a fitting analysis. Based on the proposed formulas, numerical simulation of axial compressive and tensile failure processes of concrete and cement mortar materials, respectively were conducted. The calculated results were a good match with the test results.

关键词: concrete     meso-mechanical model     discrete element method     size effect     mechanical parameter    

Facile synthesis of polyaniline nanorods to simultaneously enhance the mechanical properties and wear

《化学科学与工程前沿(英文)》 2023年 第17卷 第9期   页码 1254-1266 doi: 10.1007/s11705-023-2297-3

摘要: To enhance the mechanical properties and wear resistance of epoxy resin, polyaniline nanorods were first synthesized using a facile route, and then introduced into the epoxy matrix to yield composites via solution mixing. Several measurements were conducted to investigate the phase structures and compositions of polyaniline nanorods, and their positive influences on the mechanical and tribological properties of epoxy resin were also characterized. The results confirmed that the as-synthesized polyaniline exhibited representative rod-like morphologies and dispersed well in the epoxy matrix, leading to significant enhancements in the tensile strength and elastic modulus of epoxy composites. The highest values of 110.33 MPa and 2.04 GPa were obtained by adding 5%–7% polyaniline nanorods, which were 43% and 62% higher than the pure sample, respectively. The wear rate was increased first and then decreased along with polyaniline nanorods, presenting the lowest value of 2.12 × 10−5 mm3·Nm–1 by adding 5% filler, which was markedly reduced by ca. 70% compared to the control sample. Finally, the possible wear mechanism was proposed and discussed in detail. This study tried to broaden the applications of polyaniline nanorods in the field of tribology.

关键词: epoxy resin     polyaniline nanorods     mechanical property     tribological performance     wear mechanism    

Thermo-mechanical simulation of frost heave in saturated soils

《结构与土木工程前沿(英文)》   页码 1400-1412 doi: 10.1007/s11709-023-0990-x

摘要: Roads are exposed to various degradation mechanisms during their lifetime. The pavement deterioration caused by the surrounding environment is particularly severe in winter when the humidity and subfreezing temperatures prevail. Frost heave-induced damage is one of the winter-related pavement deterioration. It occurs when the porewater in the soil is exposed to freezing temperatures. The study of frost heave requires conducting a multiphysics analysis, considering the thermal, mechanical, and hydraulic fields. This paper presents the use of a coupled thermo-mechanical approach to simulate frost heave in saturated soils. A function predicting porosity evolution is implemented to couple the thermal and mechanical field analyses. This function indirectly considers the effect of the water seepage inside the soil. Different frost heave scenarios with uniform and non-uniform boundary conditions are considered to demonstrate the capabilities of the method. The results of the simulations indicate that the thermo-mechanical model captures various processes involved in the frost heave phenomenon, such as water fusion, porosity variation, cryogenic suction force generation, and soil expansion. The characteristics and consequences of each process are determined and discussed separately. Furthermore, the results show that non-uniform thermal boundaries and presence of a culvert inside the soil result in uneven ground surface deformations.

关键词: frost heave     multiphysics analysis     thermo-mechanical approach     saturated soils    

Electronic and mechanical responses of two-dimensional HfS

Mohammad SALAVATI

《结构与土木工程前沿(英文)》 2019年 第13卷 第2期   页码 486-494 doi: 10.1007/s11709-018-0491-5

摘要: During the last decade, numerous high-quality two-dimensional (2D) materials with semiconducting electronic character have been synthesized. Recent experimental study (Sci. Adv. 2017;3: e1700481) nevertheless confirmed that 2D ZrSe and HfSe are among the best candidates to replace the silicon in nanoelectronics owing to their moderate band-gap. We accordingly conducted first-principles calculations to explore the mechanical and electronic responses of not only ZrSe and HfSe , but also ZrS and HfS in their single-layer and free-standing form. We particularly studied the possibility of engineering of the electronic properties of these attractive 2D materials using the biaxial or uniaxial tensile loadings. The comprehensive insight provided concerning the intrinsic properties of HfS , HfSe , ZrS , and ZrSe can be useful for their future applications in nanodevices.

关键词: 2D materials     mechanical     electronic     DFT    

Experimental study on compaction-induced anisotropic mechanical property of rockfill material

Xiangtao ZHANG, Yizhao GAO, Yuan WANG, Yu-zhen YU, Xun SUN

《结构与土木工程前沿(英文)》 2021年 第15卷 第1期   页码 109-123 doi: 10.1007/s11709-021-0693-0

摘要: The anisotropy of rockfill materials has a significant influence on the performance of engineering structures. However, relevant research data are very limited, because of the difficulty with preparing specimens with different inclination angles using traditional methods. Furthermore, the anisotropy test of rockfill materials is complex and complicated, especially for triaxial tests, in which the major principal stress plane intersects with the compaction plane at different angles. In this study, the geometric characteristics of a typical particle fraction consisting of a specific rockfill material were statistically investigated, and the distribution characteristics of particle orientation in specimens prepared via different compaction methods were examined. For high-density rockfill materials, a set of specimen preparation devices for inclined compaction planes was developed, and a series of conventional triaxial compression tests with different principal stress direction angles were conducted. The results reveal that the principal stress direction angle has a significant effect on the modulus, shear strength, and dilatancy of the compacted rockfill materials. Analysis of the relationship between the principal stress direction angles, change in the stress state, and change in the corresponding dominant shear plane shows that the angle between the compacted surface and dominant shear plane is closely related to interlocking resistance associated with the particle orientation. In addition, different principal stress direction angles can change the extent of the particle interlocking effect, causing the specimen to exhibit different degrees of anisotropy.

关键词: rockfill     inclination of specimen preparation     anisotropy     mechanical property     mechanism    

Three-dimensional composite Li metal anode by simple mechanical modification for high-energy batteries

《能源前沿(英文)》 2023年 第17卷 第5期   页码 569-584 doi: 10.1007/s11708-023-0875-7

摘要: Lithium (Li) metal is believed to be the “Holy Grail” among all anode materials for next-generation Li-based batteries due to its high theoretical specific capacity (3860 mAh/g) and lowest redox potential (−3.04 V). Disappointingly, uncontrolled dendrite formation and “hostless” deposition impede its further development. It is well accepted that the construction of three-dimensional (3D) composite Li metal anode could tackle the above problems to some extent by reducing local current density and maintaining electrode volume during cycling. However, most strategies to build 3D composite Li metal anode require either electrodeposition or melt-infusion process. In spite of their effectiveness, these procedures bring multiple complex processing steps, high temperature, and harsh experimental conditions which cannot meet the actual production demand in consideration of cost and safety. Under this condition, a novel method to construct 3D composite anode via simple mechanical modification has been recently proposed which does not involve harsh conditions, fussy procedures, or fancy equipment. In this mini review, a systematic and in-depth investigation of this mechanical deformation technique to build 3D composite Li metal anode is provided. First, by summarizing a number of recent studies, different mechanical modification approaches are classified clearly according to their specific procedures. Then, the effect of each individual mechanical modification approach and its working mechanisms is reviewed. Afterwards, the merits and limits of different approaches are compared. Finally, a general summary and perspective on construction strategies for next-generation 3D composite Li anode are presented.

关键词: lithium (Li)-ion battery (LIB)     Li metal battery     three-dimensional (3D) composite Li metal anode     mechanical modification     reducing local current density    

Analysis of suitable geometrical parameters for designing a tendon-driven under-actuated mechanical finger

Francesco PENTA,Cesare ROSSI,Sergio SAVINO

《机械工程前沿(英文)》 2016年 第11卷 第2期   页码 184-194 doi: 10.1007/s11465-016-0385-y

摘要:

This study aims to optimize the geometrical parameters of an under-actuated mechanical finger by conducting a theoretical analysis of these parameters. The finger is actuated by a flexion tendon and an extension tendon. The considered parameters are the tendon guide positions with respect to the hinges. By applying such an optimization, the correct kinematical and dynamical behavior of the closing cycle of the finger can be obtained. The results of this study are useful for avoiding the snap-through and the single joint hyperflexion, which are the two breakdowns most frequently observed during experimentation on prototypes. Diagrams are established to identify the optimum values for the tendon guides position of a finger with specified dimensions. The findings of this study can serve as guide for future finger design.

关键词: tendon-driven fingers     mechanical finger design     under-actuated mechanical systems    

2023年度机械与运载工程前沿

机械与运载工程项目组

《全球工程前沿》 2023年 第7卷 第1期   页码 7-34

Introduction to the special issue on the VIII Latin-American Congress on Mechanical Engineering

Marco CECCARELLI,René-Vinicio SÁNCHEZ

《机械工程前沿(英文)》 2015年 第10卷 第3期   页码 219-220 doi: 10.1007/s11465-015-0356-8

A comparative study of the mechanical properties, fracture behavior, creep, and shrinkage of chemically

Mahdi AREZOUMANDI, Mark EZZELL, Jeffery S VOLZ

《结构与土木工程前沿(英文)》 2014年 第8卷 第1期   页码 36-45 doi: 10.1007/s11709-014-0243-0

摘要: This study presents the results of an experimental investigation that compares the mechanical properties, fracture behavior, creep, and shrinkage of a chemically-based self-consolidating concrete (SCC) mix with that of a corresponding conventional concrete (CC) mix. The CC and SCC mix designs followed conventional proportioning in terms of aggregate type and content, cement content, air content, water-cementitiuos materials ( / ) ratio, and workability. Then, using only chemical admixtures, the authors converted the CC mix to an SCC mix with all of the necessary passing, filling, flowability, and stability requirements typically found in SCC. The high fluidity was achieved with a polycarboxylate-based high-range water-reducing admixture, while the enhanced stability was accomplished with an organic, polymer-based viscosity-modifying admixture. The comparison indicated that the SCC and CC mixes had virtually identical tensile splitting strengths, flexural strengths, creep, and shrinkage. However, the SCC mix showed higher compressive strengths and fracture energies than the corresponding CC mix.

关键词: admixture     conventional concrete (CC)     creep     fracture mechanic     mechanical Properties     self-consolidating concrete (SCC)     shrinkage    

标题 作者 时间 类型 操作

Development and clinical trial of a novel bioactive bone cement

LEONG John, LI Zhaoyang, LU William

期刊论文

Sufficient downward rotation of the christa philtri on the cleft side: a modified technique

null

期刊论文

A bionic approach for the mechanical and electrical decoupling of an MEMS capacitive sensor in ultralow

期刊论文

Process evaluation of an alternating aerobic-anoxic process applied in a sequencing batch reactor for nitrogen removal

ZENG Wei, PENG Yongzhen, WANG Shuying

期刊论文

新的充分条件和哈密尔顿图

赵克文

期刊论文

Determination of mechanical parameters for elements in meso-mechanical models of concrete

Xianglin GU, Junyu JIA, Zhuolin WANG, Li HONG, Feng LIN

期刊论文

Facile synthesis of polyaniline nanorods to simultaneously enhance the mechanical properties and wear

期刊论文

Thermo-mechanical simulation of frost heave in saturated soils

期刊论文

Electronic and mechanical responses of two-dimensional HfS

Mohammad SALAVATI

期刊论文

Experimental study on compaction-induced anisotropic mechanical property of rockfill material

Xiangtao ZHANG, Yizhao GAO, Yuan WANG, Yu-zhen YU, Xun SUN

期刊论文

Three-dimensional composite Li metal anode by simple mechanical modification for high-energy batteries

期刊论文

Analysis of suitable geometrical parameters for designing a tendon-driven under-actuated mechanical finger

Francesco PENTA,Cesare ROSSI,Sergio SAVINO

期刊论文

2023年度机械与运载工程前沿

机械与运载工程项目组

期刊论文

Introduction to the special issue on the VIII Latin-American Congress on Mechanical Engineering

Marco CECCARELLI,René-Vinicio SÁNCHEZ

期刊论文

A comparative study of the mechanical properties, fracture behavior, creep, and shrinkage of chemically

Mahdi AREZOUMANDI, Mark EZZELL, Jeffery S VOLZ

期刊论文